Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells.

Radio-adaptive response of peripheral blood lymphocytes following bystander effects induced by preirradiated CHO-K1 cells using the micronucleus assay

Background: Radio-adaptive response and bystander effects are known phenomena occurring in cells following exposure to ionizing radiation (IR). In this study we examined possible radio-adaptation of lymphocytes following bystander effects induced by CHO-K1 cells. Materials and Methods: Whole blood and CHO-K1 cells were cultured in RPMI-1640 complete medium. Cells were separately irradiated with...

Radiation Induced Bystander Effect

Introduction: Radiation effects observed in cells that are not irradiated are known as non-targeted effects.  Radiation induced bystander effect (RIBE) as a kind of non-targeted effect has been introduced in recent  years.  RIBE  occurs  in  unexposed  cells  which  are  related  to  adjacent  or  distant  irradiated  cells.  RIBE  contradict with "target theory" which necessitates radiation tr...

The Role of Target and Bystander Cells in Dose-Response Relationship of Radiation-Induced Bystander Effects in Two Cell Lines

The role of dose fractionation in the level of Radiation- Induced Bystander Effect in QU-DB Cells

Introduction: Radiation effects induced in non-irradiated cells are termed radiation- induced bystander effects (RIBE). The present study intends to examine the RIBE response of QU-DB bystander cells to first, second and third radiation fractions and compare their cumulative outcome with an equal, single acute dose.   Materials and Methods: This experimental ...

Induction of apoptosis by 900 MHz radiofrequency radiation emitted from a GSM mobile phone simulator in bystander Jurkat cells

Background: Radiation-induced bystander effect is a response which results in damage in non-irradiated cells in response to signals from the irradiated cells. The aim of the present study was to investigate microwave-induced bystander effect from a GSM mobile phone simulator on induction of apoptosis in Jurkat cell line. Materials and Methods: Jurkat cells were divided into three groups of non-...